| Fort Pierce to Smyrna (Delaware) | 863.96 mi (1,390.41 km) |
| Fort Pierce to Smyrna (Georgia) | 509.19 mi (819.45 km) |
| Fort Pierce to Smyrna (Tennessee) | 692.82 mi (1,114.98 km) |
| Fort Pierce to Snellville (Georgia) | 494.64 mi (796.05 km) |
| Fort Pierce to Snoqualmie (Washington) | 2,621.58 mi (4,219.02 km) |
| Fort Pierce to Snyder (Texas) | 1,280.56 mi (2,060.86 km) |
| Fort Pierce to Socastee (South Carolina) | 439.85 mi (707.86 km) |
| Fort Pierce to Socorro (Texas) | 1,581.10 mi (2,544.54 km) |
| Fort Pierce to Soddy-Daisy (Tennessee) | 611.38 mi (983.92 km) |
| Fort Pierce to Solana Beach (California) | 2,225.93 mi (3,582.29 km) |
| Fort Pierce to Soledad (California) | 2,463.82 mi (3,965.13 km) |
| Fort Pierce to Solon (Ohio) | 966.61 mi (1,555.61 km) |
| Fort Pierce to Somers Point (New Jersey) | 885.25 mi (1,424.66 km) |
| Fort Pierce to Somerset (Kentucky) | 712.14 mi (1,146.07 km) |
| Fort Pierce to Somerset (New Jersey) | 963.32 mi (1,550.31 km) |
