| Fort Pierce to Scottsboro (Alabama) | 602.09 mi (968.97 km) |
| Fort Pierce to Scottsdale (Arizona) | 1,916.80 mi (3,084.78 km) |
| Fort Pierce to Scranton (Pennsylvania) | 1,001.55 mi (1,611.84 km) |
| Fort Pierce to Seabrook (Maryland) | 823.30 mi (1,324.97 km) |
| Fort Pierce to Seabrook (Texas) | 903.04 mi (1,453.30 km) |
| Fort Pierce to Seaford (New York) | 994.63 mi (1,600.70 km) |
| Fort Pierce to Seagoville (Texas) | 1,032.84 mi (1,662.20 km) |
| Fort Pierce to Seal Beach (California) | 2,273.25 mi (3,658.44 km) |
| Fort Pierce to Searcy (Arkansas) | 861.26 mi (1,386.07 km) |
| Fort Pierce to Seaside (California) | 2,490.86 mi (4,008.66 km) |
| Fort Pierce to SeaTac (Washington) | 2,640.35 mi (4,249.24 km) |
| Fort Pierce to Seattle (Washington) | 2,644.97 mi (4,256.67 km) |
| Fort Pierce to Sebastian (Florida) | 26.07 mi (41.96 km) |
| Fort Pierce to Sebring (Florida) | 68.14 mi (109.67 km) |
| Fort Pierce to Secaucus (New Jersey) | 989.47 mi (1,592.40 km) |
