| Fort Pierce to Santa Rosa (California) | 2,547.21 mi (4,099.34 km) |
| Fort Pierce to Santaquin (Utah) | 1,990.86 mi (3,203.98 km) |
| Fort Pierce to Santee (California) | 2,210.14 mi (3,556.88 km) |
| Fort Pierce to Sapulpa (Oklahoma) | 1,097.49 mi (1,766.23 km) |
| Fort Pierce to Saraland (Alabama) | 524.29 mi (843.76 km) |
| Fort Pierce to Sarasota (Florida) | 135.11 mi (217.44 km) |
| Fort Pierce to Sarasota Springs (Florida) | 131.04 mi (210.88 km) |
| Fort Pierce to Saratoga (California) | 2,504.59 mi (4,030.74 km) |
| Fort Pierce to Saratoga Springs (New York) | 1,141.53 mi (1,837.11 km) |
| Fort Pierce to Saratoga Springs (Utah) | 2,004.28 mi (3,225.57 km) |
| Fort Pierce to Sartell (Minnesota) | 1,469.55 mi (2,365.01 km) |
| Fort Pierce to Satellite Beach (Florida) | 54.36 mi (87.48 km) |
| Fort Pierce to Sauk Rapids (Minnesota) | 1,466.50 mi (2,360.10 km) |
| Fort Pierce to Sault Ste. Marie (Michigan) | 1,334.85 mi (2,148.24 km) |
| Fort Pierce to Savage (Minnesota) | 1,396.69 mi (2,247.75 km) |
