| Fort Pierce to Elyria (Ohio) | 969.05 mi (1,559.53 km) |
| Fort Pierce to Emeryville (California) | 2,521.70 mi (4,058.29 km) |
| Fort Pierce to Emmaus (Pennsylvania) | 946.95 mi (1,523.97 km) |
| Fort Pierce to Emporia (Kansas) | 1,188.70 mi (1,913.03 km) |
| Fort Pierce to Encinitas (California) | 2,226.14 mi (3,582.63 km) |
| Fort Pierce to Endicott (New York) | 1,042.08 mi (1,677.07 km) |
| Fort Pierce to Endwell (New York) | 1,043.99 mi (1,680.14 km) |
| Fort Pierce to Englewood (Colorado) | 1,643.53 mi (2,645.01 km) |
| Fort Pierce to Englewood (Florida) | 127.40 mi (205.02 km) |
| Fort Pierce to Englewood (New Jersey) | 998.40 mi (1,606.77 km) |
| Fort Pierce to Englewood (Ohio) | 888.90 mi (1,430.54 km) |
| Fort Pierce to Enid (Oklahoma) | 1,197.77 mi (1,927.62 km) |
| Fort Pierce to Ennis (Texas) | 1,031.77 mi (1,660.47 km) |
| Fort Pierce to Ensley (Florida) | 470.35 mi (756.95 km) |
| Fort Pierce to Enterprise (Alabama) | 427.05 mi (687.27 km) |
