| Fort Madison to Olympia Heights (Florida) | 1,208.04 mi (1,944.16 km) |
| Fort Madison to Omaha (Nebraska) | 249.35 mi (401.29 km) |
| Fort Madison to On Top of the World Designated Place (Florida) | 945.88 mi (1,522.24 km) |
| Fort Madison to Onalaska (Wisconsin) | 225.89 mi (363.53 km) |
| Fort Madison to Oneida (New York) | 823.80 mi (1,325.78 km) |
| Fort Madison to Oneonta (New York) | 850.31 mi (1,368.44 km) |
| Fort Madison to Ontario (California) | 1,505.89 mi (2,423.49 km) |
| Fort Madison to Ontario (Oregon) | 1,324.44 mi (2,131.49 km) |
| Fort Madison to Opa-locka (Florida) | 1,199.96 mi (1,931.15 km) |
| Fort Madison to Opelika (Alabama) | 641.58 mi (1,032.53 km) |
| Fort Madison to Opelousas (Louisiana) | 698.73 mi (1,124.50 km) |
| Fort Madison to Orange (California) | 1,524.04 mi (2,452.70 km) |
| Fort Madison to Orange (Texas) | 737.86 mi (1,187.47 km) |
| Fort Madison to Orange City (Florida) | 987.42 mi (1,589.10 km) |
| Fort Madison to Orangeburg (South Carolina) | 758.42 mi (1,220.56 km) |
