| Fort Lauderdale to Southern Pines (North Carolina) | 626.95 mi (1,008.97 km) |
| Fort Lauderdale to Southfield (Michigan) | 1,142.34 mi (1,838.42 km) |
| Fort Lauderdale to Southgate (Michigan) | 1,123.36 mi (1,807.87 km) |
| Fort Lauderdale to Southlake (Texas) | 1,123.35 mi (1,807.86 km) |
| Fort Lauderdale to Spanaway (Washington) | 2,708.73 mi (4,359.27 km) |
| Fort Lauderdale to Spanish Fork (Utah) | 2,046.80 mi (3,294.01 km) |
| Fort Lauderdale to Spanish Lake (Missouri) | 1,050.83 mi (1,691.15 km) |
| Fort Lauderdale to Spanish Springs (Nevada) | 2,451.60 mi (3,945.48 km) |
| Fort Lauderdale to Sparks (Nevada) | 2,453.04 mi (3,947.79 km) |
| Fort Lauderdale to Spartanburg (South Carolina) | 617.33 mi (993.50 km) |
| Fort Lauderdale to Spearfish (South Dakota) | 1,827.88 mi (2,941.69 km) |
| Fort Lauderdale to Speedway (Indiana) | 1,006.74 mi (1,620.20 km) |
| Fort Lauderdale to Spencer (Iowa) | 1,447.01 mi (2,328.73 km) |
| Fort Lauderdale to Spokane (Washington) | 2,502.99 mi (4,028.17 km) |
| Fort Lauderdale to Spokane Valley (Washington) | 2,494.37 mi (4,014.31 km) |
