| Eugene to Enterprise (Nevada) | 694.52 mi (1,117.72 km) |
| Eugene to Enumclaw (Washington) | 224.05 mi (360.57 km) |
| Eugene to Ephrata (Pennsylvania) | 2,387.68 mi (3,842.60 km) |
| Eugene to Erie (Colorado) | 965.84 mi (1,554.36 km) |
| Eugene to Erie (Pennsylvania) | 2,151.34 mi (3,462.25 km) |
| Eugene to Erlanger (Kentucky) | 2,004.34 mi (3,225.67 km) |
| Eugene to Escanaba (Michigan) | 1,752.09 mi (2,819.72 km) |
| Eugene to Escondido (California) | 821.60 mi (1,322.23 km) |
| Eugene to Española (New Mexico) | 1,056.59 mi (1,700.42 km) |
| Eugene to Essex (Maryland) | 2,398.30 mi (3,859.69 km) |
| Eugene to Essex Junction (Vermont) | 2,434.33 mi (3,917.68 km) |
| Eugene to Estelle (Louisiana) | 2,051.20 mi (3,301.09 km) |
| Eugene to Estero (Florida) | 2,594.61 mi (4,175.62 km) |
| Eugene to Euclid (Ohio) | 2,092.50 mi (3,367.55 km) |
| Eugene to Eufaula (Alabama) | 2,207.56 mi (3,552.72 km) |
