| Escondido to Southern Pines (North Carolina) | 2,145.37 mi (3,452.64 km) |
| Escondido to Southfield (Michigan) | 1,940.23 mi (3,122.51 km) |
| Escondido to Southgate (Michigan) | 1,940.44 mi (3,122.83 km) |
| Escondido to Southlake (Texas) | 1,152.15 mi (1,854.21 km) |
| Escondido to Spanaway (Washington) | 1,004.70 mi (1,616.91 km) |
| Escondido to Spanish Fork (Utah) | 568.05 mi (914.18 km) |
| Escondido to Spanish Lake (Missouri) | 1,546.16 mi (2,488.31 km) |
| Escondido to Spanish Springs (Nevada) | 473.15 mi (761.45 km) |
| Escondido to Sparks (Nevada) | 468.51 mi (753.99 km) |
| Escondido to Spartanburg (South Carolina) | 2,005.90 mi (3,228.18 km) |
| Escondido to Spearfish (South Dakota) | 1,057.93 mi (1,702.57 km) |
| Escondido to Speedway (Indiana) | 1,763.87 mi (2,838.68 km) |
| Escondido to Spencer (Iowa) | 1,371.24 mi (2,206.80 km) |
| Escondido to Spokane (Washington) | 1,004.26 mi (1,616.20 km) |
| Escondido to Spokane Valley (Washington) | 1,003.81 mi (1,615.48 km) |
