| Escanaba to Southern Pines (North Carolina) | 832.76 mi (1,340.20 km) |
| Escanaba to Southfield (Michigan) | 295.18 mi (475.04 km) |
| Escanaba to Southgate (Michigan) | 311.73 mi (501.68 km) |
| Escanaba to Southlake (Texas) | 1,032.62 mi (1,661.84 km) |
| Escanaba to Spanaway (Washington) | 1,671.08 mi (2,689.35 km) |
| Escanaba to Spanish Fork (Utah) | 1,295.69 mi (2,085.22 km) |
| Escanaba to Spanish Lake (Missouri) | 506.47 mi (815.08 km) |
| Escanaba to Spanish Springs (Nevada) | 1,694.15 mi (2,726.47 km) |
| Escanaba to Sparks (Nevada) | 1,698.85 mi (2,734.03 km) |
| Escanaba to Spartanburg (South Carolina) | 794.01 mi (1,277.83 km) |
| Escanaba to Spearfish (South Dakota) | 818.54 mi (1,317.31 km) |
| Escanaba to Speedway (Indiana) | 413.58 mi (665.60 km) |
| Escanaba to Spencer (Iowa) | 436.18 mi (701.96 km) |
| Escanaba to Spokane (Washington) | 1,434.47 mi (2,308.55 km) |
| Escanaba to Spokane Valley (Washington) | 1,425.32 mi (2,293.83 km) |
