| Erie to Olympia Heights (Florida) | 1,132.73 mi (1,822.95 km) |
| Erie to Omaha (Nebraska) | 825.38 mi (1,328.32 km) |
| Erie to On Top of the World Designated Place (Florida) | 907.43 mi (1,460.37 km) |
| Erie to Onalaska (Wisconsin) | 575.29 mi (925.83 km) |
| Erie to Oneida (New York) | 233.93 mi (376.47 km) |
| Erie to Oneonta (New York) | 256.95 mi (413.51 km) |
| Erie to Ontario (California) | 2,097.87 mi (3,376.20 km) |
| Erie to Ontario (Oregon) | 1,851.67 mi (2,979.97 km) |
| Erie to Opa-locka (Florida) | 1,120.53 mi (1,803.32 km) |
| Erie to Opelika (Alabama) | 714.87 mi (1,150.46 km) |
| Erie to Opelousas (Louisiana) | 1,041.03 mi (1,675.37 km) |
| Erie to Orange (California) | 2,116.23 mi (3,405.74 km) |
| Erie to Orange (Texas) | 1,124.20 mi (1,809.23 km) |
| Erie to Orange City (Florida) | 913.31 mi (1,469.83 km) |
| Erie to Orangeburg (South Carolina) | 597.42 mi (961.45 km) |
