| Enniskillen to Southern Pines (North Carolina) | 3,584.36 mi (5,768.47 km) |
| Enniskillen to Southfield (Michigan) | 3,388.72 mi (5,453.62 km) |
| Enniskillen to Southgate (Michigan) | 3,399.12 mi (5,470.36 km) |
| Enniskillen to Southlake (Texas) | 4,387.55 mi (7,061.08 km) |
| Enniskillen to Spanaway (Washington) | 4,463.79 mi (7,183.77 km) |
| Enniskillen to Spanish Fork (Utah) | 4,521.57 mi (7,276.77 km) |
| Enniskillen to Spanish Lake (Missouri) | 3,828.10 mi (6,160.72 km) |
| Enniskillen to Spanish Springs (Nevada) | 4,801.94 mi (7,727.97 km) |
| Enniskillen to Sparks (Nevada) | 4,808.07 mi (7,737.84 km) |
| Enniskillen to Spartanburg (South Carolina) | 3,696.54 mi (5,949.01 km) |
| Enniskillen to Spearfish (South Dakota) | 4,031.80 mi (6,488.56 km) |
| Enniskillen to Speedway (Indiana) | 3,628.70 mi (5,839.82 km) |
| Enniskillen to Spencer (Iowa) | 3,797.53 mi (6,111.54 km) |
| Enniskillen to Spokane (Washington) | 4,291.59 mi (6,906.64 km) |
| Enniskillen to Spokane Valley (Washington) | 4,286.10 mi (6,897.80 km) |
