| Enniskillen to Enumclaw (Washington) | 4,446.01 mi (7,155.16 km) |
| Enniskillen to Ephrata (Pennsylvania) | 3,219.31 mi (5,180.97 km) |
| Enniskillen to Erie (Colorado) | 4,302.72 mi (6,924.56 km) |
| Enniskillen to Erie (Pennsylvania) | 3,282.86 mi (5,283.25 km) |
| Enniskillen to Erlanger (Kentucky) | 3,602.40 mi (5,797.50 km) |
| Enniskillen to Escanaba (Michigan) | 3,383.42 mi (5,445.10 km) |
| Enniskillen to Escondido (California) | 5,087.75 mi (8,187.94 km) |
| Enniskillen to Española (New Mexico) | 4,552.42 mi (7,326.42 km) |
| Enniskillen to Essex (Maryland) | 3,270.37 mi (5,263.15 km) |
| Enniskillen to Essex Junction (Vermont) | 2,908.56 mi (4,680.87 km) |
| Enniskillen to Estelle (Louisiana) | 4,278.38 mi (6,885.39 km) |
| Enniskillen to Estero (Florida) | 4,126.62 mi (6,641.15 km) |
| Enniskillen to Euclid (Ohio) | 3,362.70 mi (5,411.74 km) |
| Enniskillen to Eufaula (Alabama) | 3,976.62 mi (6,399.75 km) |
| Enniskillen to Eugene (Oregon) | 4,654.69 mi (7,491.00 km) |
