| Enniskillen to Shotley Bridge | 234.02 mi (376.61 km) |
| Enniskillen to Shrewsbury | 230.24 mi (370.53 km) |
| Enniskillen to Sidcup | 380.24 mi (611.94 km) |
| Enniskillen to Sidmouth | 313.47 mi (504.48 km) |
| Enniskillen to Sileby | 290.36 mi (467.29 km) |
| Enniskillen to Sittingbourne | 406.28 mi (653.84 km) |
| Enniskillen to Skegness | 336.33 mi (541.27 km) |
| Enniskillen to Skelmersdale | 205.18 mi (330.20 km) |
| Enniskillen to Skipton | 228.97 mi (368.49 km) |
| Enniskillen to Sleaford | 309.95 mi (498.81 km) |
| Enniskillen to Slough | 352.81 mi (567.79 km) |
| Enniskillen to Small Heath | 271.33 mi (436.66 km) |
| Enniskillen to Smethwick | 266.13 mi (428.29 km) |
| Enniskillen to Snaresbrook | 370.84 mi (596.82 km) |
| Enniskillen to Snodland | 396.30 mi (637.79 km) |
