| Effingham to Smyrna (Delaware) | 692.43 mi (1,114.37 km) |
| Effingham to Smyrna (Georgia) | 426.68 mi (686.67 km) |
| Effingham to Smyrna (Tennessee) | 244.37 mi (393.27 km) |
| Effingham to Snellville (Georgia) | 442.68 mi (712.43 km) |
| Effingham to Snoqualmie (Washington) | 1,755.41 mi (2,825.07 km) |
| Effingham to Snyder (Texas) | 820.03 mi (1,319.71 km) |
| Effingham to Socastee (South Carolina) | 649.41 mi (1,045.13 km) |
| Effingham to Socorro (Texas) | 1,120.85 mi (1,803.83 km) |
| Effingham to Soddy-Daisy (Tennessee) | 325.22 mi (523.39 km) |
| Effingham to Solana Beach (California) | 1,650.75 mi (2,656.63 km) |
| Effingham to Soledad (California) | 1,790.46 mi (2,881.46 km) |
| Effingham to Solon (Ohio) | 406.18 mi (653.68 km) |
| Effingham to Somers Point (New Jersey) | 745.81 mi (1,200.27 km) |
| Effingham to Somerset (Kentucky) | 256.28 mi (412.44 km) |
| Effingham to Somerset (New Jersey) | 750.98 mi (1,208.59 km) |
