| Effingham to Sanford (Maine) | 968.45 mi (1,558.57 km) |
| Effingham to Sanford (North Carolina) | 572.68 mi (921.63 km) |
| Effingham to Sanger (California) | 1,690.29 mi (2,720.26 km) |
| Effingham to Santa Ana (California) | 1,664.70 mi (2,679.08 km) |
| Effingham to Santa Barbara (California) | 1,746.32 mi (2,810.42 km) |
| Effingham to Santa Clara (California) | 1,807.23 mi (2,908.46 km) |
| Effingham to Santa Clara (Oregon) | 1,805.54 mi (2,905.74 km) |
| Effingham to Santa Clarita (California) | 1,680.99 mi (2,705.30 km) |
| Effingham to Santa Cruz (California) | 1,817.51 mi (2,925.00 km) |
| Effingham to Santa Fe (New Mexico) | 984.55 mi (1,584.48 km) |
| Effingham to Santa Fe (Texas) | 768.86 mi (1,237.36 km) |
| Effingham to Santa Fe Springs (California) | 1,669.46 mi (2,686.74 km) |
| Effingham to Santa Maria (California) | 1,773.50 mi (2,854.17 km) |
| Effingham to Santa Monica (California) | 1,689.64 mi (2,719.21 km) |
| Effingham to Santa Paula (California) | 1,712.98 mi (2,756.77 km) |
