| Effingham to Reidsville (North Carolina) | 521.60 mi (839.43 km) |
| Effingham to Reisterstown (Maryland) | 627.63 mi (1,010.07 km) |
| Effingham to Rendon (Texas) | 663.32 mi (1,067.51 km) |
| Effingham to Reno (Nevada) | 1,664.30 mi (2,678.44 km) |
| Effingham to Renton (Washington) | 1,771.25 mi (2,850.55 km) |
| Effingham to Republic (Missouri) | 298.87 mi (480.99 km) |
| Effingham to Reston (Virginia) | 601.08 mi (967.35 km) |
| Effingham to Revere (Massachusetts) | 944.15 mi (1,519.46 km) |
| Effingham to Rexburg (Idaho) | 1,241.67 mi (1,998.28 km) |
| Effingham to Reynoldsburg (Ohio) | 312.09 mi (502.27 km) |
| Effingham to Rialto (California) | 1,628.89 mi (2,621.45 km) |
| Effingham to Richardson (Texas) | 622.56 mi (1,001.92 km) |
| Effingham to Richfield (Minnesota) | 465.84 mi (749.70 km) |
| Effingham to Richfield (Wisconsin) | 284.89 mi (458.49 km) |
| Effingham to Richland (Washington) | 1,625.79 mi (2,616.45 km) |
