| Effingham to Medford (New York) | 831.39 mi (1,337.99 km) |
| Effingham to Medford (Oregon) | 1,797.48 mi (2,892.76 km) |
| Effingham to Medina (Ohio) | 379.31 mi (610.45 km) |
| Effingham to Medulla (Florida) | 858.34 mi (1,381.37 km) |
| Effingham to Mehlville (Missouri) | 104.15 mi (167.61 km) |
| Effingham to Melbourne (Florida) | 885.06 mi (1,424.36 km) |
| Effingham to Melissa (Texas) | 600.85 mi (966.98 km) |
| Effingham to Melrose (Massachusetts) | 941.73 mi (1,515.57 km) |
| Effingham to Melrose Park (Illinois) | 195.61 mi (314.80 km) |
| Effingham to Melville (New York) | 809.15 mi (1,302.21 km) |
| Effingham to Melvindale (Michigan) | 356.06 mi (573.02 km) |
| Effingham to Memphis (Florida) | 870.88 mi (1,401.55 km) |
| Effingham to Memphis (Tennessee) | 287.94 mi (463.39 km) |
| Effingham to Menasha (Wisconsin) | 351.88 mi (566.30 km) |
| Effingham to Mendota (California) | 1,733.10 mi (2,789.16 km) |
