| Effingham to McKeesport (Pennsylvania) | 470.08 mi (756.52 km) |
| Effingham to McKinleyville (California) | 1,871.14 mi (3,011.31 km) |
| Effingham to McKinney (Texas) | 609.61 mi (981.08 km) |
| Effingham to McLean (Virginia) | 609.25 mi (980.49 km) |
| Effingham to McMinnville (Oregon) | 1,808.38 mi (2,910.30 km) |
| Effingham to McMinnville (Tennessee) | 281.76 mi (453.45 km) |
| Effingham to McNair (Virginia) | 597.57 mi (961.70 km) |
| Effingham to McPherson (Kansas) | 493.41 mi (794.06 km) |
| Effingham to Mead Valley (California) | 1,630.36 mi (2,623.81 km) |
| Effingham to Meadow Woods (Florida) | 849.60 mi (1,367.30 km) |
| Effingham to Meadowbrook (Virginia) | 611.66 mi (984.37 km) |
| Effingham to Meadville (Pennsylvania) | 475.26 mi (764.86 km) |
| Effingham to Mebane (North Carolina) | 549.09 mi (883.68 km) |
| Effingham to Mechanicsville (Virginia) | 614.71 mi (989.28 km) |
| Effingham to Medford (Massachusetts) | 938.91 mi (1,511.02 km) |
