| Effingham to Euless (Texas) | 643.67 mi (1,035.88 km) |
| Effingham to Eureka (California) | 1,876.30 mi (3,019.62 km) |
| Effingham to Eureka (Missouri) | 120.81 mi (194.43 km) |
| Effingham to Eustis (Florida) | 810.54 mi (1,304.44 km) |
| Effingham to Evans (Colorado) | 863.10 mi (1,389.03 km) |
| Effingham to Evans (Georgia) | 524.11 mi (843.48 km) |
| Effingham to Evanston (Illinois) | 207.09 mi (333.28 km) |
| Effingham to Evanston (Wyoming) | 1,188.86 mi (1,913.28 km) |
| Effingham to Evansville (Indiana) | 95.60 mi (153.86 km) |
| Effingham to Everett (Massachusetts) | 941.48 mi (1,515.16 km) |
| Effingham to Everett (Washington) | 1,774.14 mi (2,855.20 km) |
| Effingham to Evergreen Park (Illinois) | 185.17 mi (298.00 km) |
| Effingham to Ewa Beach (Hawaii) | 4,222.86 mi (6,796.04 km) |
| Effingham to Ewa Gentry (Hawaii) | 4,223.24 mi (6,796.66 km) |
| Effingham to Excelsior Springs (Missouri) | 304.81 mi (490.54 km) |
