| Effingham to El Sobrante (California) | 1,638.86 mi (2,637.48 km) |
| Effingham to Eldersburg (Maryland) | 620.33 mi (998.33 km) |
| Effingham to Elfers (Florida) | 824.23 mi (1,326.47 km) |
| Effingham to Elgin (Illinois) | 201.95 mi (325.01 km) |
| Effingham to Elizabeth (New Jersey) | 767.79 mi (1,235.63 km) |
| Effingham to Elizabeth City (North Carolina) | 700.27 mi (1,126.97 km) |
| Effingham to Elizabethton (Tennessee) | 394.89 mi (635.51 km) |
| Effingham to Elizabethtown (Kentucky) | 174.75 mi (281.23 km) |
| Effingham to Elizabethtown (Pennsylvania) | 639.45 mi (1,029.09 km) |
| Effingham to Elk City (Oklahoma) | 651.01 mi (1,047.69 km) |
| Effingham to Elk Grove (California) | 1,759.74 mi (2,832.02 km) |
| Effingham to Elk Grove Village (Illinois) | 201.54 mi (324.35 km) |
| Effingham to Elk Plain (Washington) | 1,776.21 mi (2,858.53 km) |
| Effingham to Elk River (Minnesota) | 499.78 mi (804.31 km) |
| Effingham to Elkhart (Indiana) | 223.81 mi (360.18 km) |
