| Effingham to Duluth (Minnesota) | 559.02 mi (899.66 km) |
| Effingham to Dumas (Texas) | 768.19 mi (1,236.29 km) |
| Effingham to Dumont (New Jersey) | 779.50 mi (1,254.48 km) |
| Effingham to Duncan (Oklahoma) | 606.70 mi (976.38 km) |
| Effingham to Duncanville (Texas) | 646.91 mi (1,041.11 km) |
| Effingham to Dundalk (Maryland) | 645.21 mi (1,038.36 km) |
| Effingham to Dunedin (Florida) | 834.37 mi (1,342.78 km) |
| Effingham to Dunkirk (New York) | 534.72 mi (860.55 km) |
| Effingham to Dunmore (Pennsylvania) | 699.84 mi (1,126.28 km) |
| Effingham to Dunwoody (Georgia) | 428.14 mi (689.02 km) |
| Effingham to Durango (Colorado) | 1,055.28 mi (1,698.31 km) |
| Effingham to Durant (Oklahoma) | 560.69 mi (902.34 km) |
| Effingham to Durham (North Carolina) | 570.99 mi (918.92 km) |
| Effingham to Dyer (Indiana) | 173.18 mi (278.70 km) |
| Effingham to Dyersburg (Tennessee) | 217.16 mi (349.49 km) |
