| Effingham to Delaware (Ohio) | 301.99 mi (486.01 km) |
| Effingham to Delhi (California) | 1,742.65 mi (2,804.52 km) |
| Effingham to Delray Beach (Florida) | 1,002.48 mi (1,613.33 km) |
| Effingham to Deltona (Florida) | 820.72 mi (1,320.82 km) |
| Effingham to Deming (New Mexico) | 1,173.99 mi (1,889.35 km) |
| Effingham to Denison (Texas) | 579.23 mi (932.18 km) |
| Effingham to Dent (Ohio) | 208.50 mi (335.55 km) |
| Effingham to Denton (Texas) | 628.71 mi (1,011.82 km) |
| Effingham to Dentsville (South Carolina) | 546.50 mi (879.51 km) |
| Effingham to Denver (Colorado) | 871.00 mi (1,401.74 km) |
| Effingham to Depew (New York) | 575.79 mi (926.64 km) |
| Effingham to Derby (Connecticut) | 828.93 mi (1,334.03 km) |
| Effingham to Derby (Kansas) | 483.71 mi (778.46 km) |
| Effingham to Des Moines (Iowa) | 315.65 mi (507.99 km) |
| Effingham to Des Moines (Washington) | 1,776.32 mi (2,858.72 km) |
