| Effingham to Crawfordsville (Indiana) | 108.68 mi (174.90 km) |
| Effingham to Crest Hill (Illinois) | 170.97 mi (275.15 km) |
| Effingham to Crestview (Florida) | 589.15 mi (948.14 km) |
| Effingham to Crestwood (Illinois) | 179.60 mi (289.04 km) |
| Effingham to Crestwood (Missouri) | 105.77 mi (170.23 km) |
| Effingham to Creve Coeur (Missouri) | 106.57 mi (171.51 km) |
| Effingham to Crofton (Maryland) | 636.40 mi (1,024.18 km) |
| Effingham to Crossville (Tennessee) | 291.72 mi (469.48 km) |
| Effingham to Crowley (Louisiana) | 652.22 mi (1,049.64 km) |
| Effingham to Crowley (Texas) | 668.43 mi (1,075.74 km) |
| Effingham to Crown Point (Indiana) | 170.74 mi (274.79 km) |
| Effingham to Crystal (Minnesota) | 477.25 mi (768.06 km) |
| Effingham to Crystal Lake (Illinois) | 215.37 mi (346.61 km) |
| Effingham to Cudahy (California) | 1,675.17 mi (2,695.92 km) |
| Effingham to Cudahy (Wisconsin) | 266.77 mi (429.33 km) |
