| Effingham to Channelview (Texas) | 744.66 mi (1,198.41 km) |
| Effingham to Chantilly (Virginia) | 596.14 mi (959.39 km) |
| Effingham to Chaparral (New Mexico) | 1,113.40 mi (1,791.85 km) |
| Effingham to Chapel Hill (North Carolina) | 565.63 mi (910.29 km) |
| Effingham to Charleston (Illinois) | 32.07 mi (51.62 km) |
| Effingham to Charleston (South Carolina) | 647.51 mi (1,042.07 km) |
| Effingham to Charleston (West Virginia) | 376.59 mi (606.07 km) |
| Effingham to Charlotte (North Carolina) | 503.47 mi (810.26 km) |
| Effingham to Charlottesville (Virginia) | 548.50 mi (882.73 km) |
| Effingham to Chaska (Minnesota) | 471.37 mi (758.60 km) |
| Effingham to Chatham (Illinois) | 71.97 mi (115.83 km) |
| Effingham to Chattanooga (Tennessee) | 334.02 mi (537.56 km) |
| Effingham to Cheat Lake (West Virginia) | 465.60 mi (749.30 km) |
| Effingham to Chelsea (Alabama) | 414.39 mi (666.89 km) |
| Effingham to Chelsea (Massachusetts) | 942.49 mi (1,516.79 km) |
