| Effingham to Candler-McAfee (Georgia) | 441.99 mi (711.31 km) |
| Effingham to Caño Martin Peña (Puerto Rico) | 1,963.65 mi (3,160.19 km) |
| Effingham to Cañon City (Colorado) | 897.79 mi (1,444.85 km) |
| Effingham to Canóvanas (Puerto Rico) | 1,973.10 mi (3,175.40 km) |
| Effingham to Canton (Georgia) | 404.90 mi (651.63 km) |
| Effingham to Canton (Illinois) | 127.21 mi (204.73 km) |
| Effingham to Canton (Mississippi) | 458.24 mi (737.46 km) |
| Effingham to Canton (Ohio) | 397.73 mi (640.08 km) |
| Effingham to Canyon (Texas) | 789.43 mi (1,270.47 km) |
| Effingham to Canyon Lake (California) | 1,632.78 mi (2,627.70 km) |
| Effingham to Canyon Lake (Texas) | 843.72 mi (1,357.83 km) |
| Effingham to Cape Coral (Florida) | 941.50 mi (1,515.19 km) |
| Effingham to Cape Girardeau (Missouri) | 136.50 mi (219.67 km) |
| Effingham to Carbondale (Illinois) | 103.26 mi (166.17 km) |
| Effingham to Carlisle (Pennsylvania) | 607.75 mi (978.08 km) |
