| Edwardsville to Wayne (Michigan) | 421.80 mi (678.82 km) |
| Edwardsville to Waynesboro (Pennsylvania) | 666.30 mi (1,072.31 km) |
| Edwardsville to Waynesboro (Virginia) | 601.75 mi (968.42 km) |
| Edwardsville to Weatherford (Oklahoma) | 528.75 mi (850.95 km) |
| Edwardsville to Weatherford (Texas) | 603.31 mi (970.93 km) |
| Edwardsville to Webb City (Missouri) | 269.34 mi (433.47 km) |
| Edwardsville to Webster (Texas) | 703.56 mi (1,132.27 km) |
| Edwardsville to Webster Groves (Missouri) | 24.36 mi (39.21 km) |
| Edwardsville to Weddington (North Carolina) | 573.13 mi (922.37 km) |
| Edwardsville to Weigelstown (Pennsylvania) | 706.73 mi (1,137.37 km) |
| Edwardsville to Weirton (West Virginia) | 513.49 mi (826.38 km) |
| Edwardsville to Wekiwa Springs (Florida) | 852.51 mi (1,371.98 km) |
| Edwardsville to Welby (Colorado) | 802.97 mi (1,292.26 km) |
| Edwardsville to Wellington (Colorado) | 807.61 mi (1,299.72 km) |
| Edwardsville to Wellington (Florida) | 1,010.18 mi (1,625.73 km) |
