| Edwardsville to The Villages (Florida) | 822.29 mi (1,323.35 km) |
| Edwardsville to The Woodlands (Texas) | 673.17 mi (1,083.37 km) |
| Edwardsville to Thibodaux (Louisiana) | 623.44 mi (1,003.32 km) |
| Edwardsville to Thomasville (Georgia) | 646.25 mi (1,040.03 km) |
| Edwardsville to Thomasville (North Carolina) | 579.81 mi (933.12 km) |
| Edwardsville to Thonotosassa (Florida) | 864.19 mi (1,390.78 km) |
| Edwardsville to Thornton (Colorado) | 801.88 mi (1,290.49 km) |
| Edwardsville to Thousand Oaks (California) | 1,628.72 mi (2,621.18 km) |
| Edwardsville to Three Lakes (Florida) | 1,066.04 mi (1,715.63 km) |
| Edwardsville to Tiffin (Ohio) | 394.52 mi (634.92 km) |
| Edwardsville to Tifton (Georgia) | 624.13 mi (1,004.44 km) |
| Edwardsville to Tigard (Oregon) | 1,729.21 mi (2,782.90 km) |
| Edwardsville to Tillmans Corner (Alabama) | 576.13 mi (927.19 km) |
| Edwardsville to Timberlake (Virginia) | 592.74 mi (953.93 km) |
| Edwardsville to Timberlane (Louisiana) | 615.91 mi (991.21 km) |
