| Edwardsville to Sugar Hill (Georgia) | 461.77 mi (743.14 km) |
| Edwardsville to Sugar Land (Texas) | 712.45 mi (1,146.59 km) |
| Edwardsville to Sugarland Run (Virginia) | 677.67 mi (1,090.60 km) |
| Edwardsville to Sugarmill Woods (Florida) | 816.75 mi (1,314.44 km) |
| Edwardsville to Suisun City (California) | 1,722.53 mi (2,772.15 km) |
| Edwardsville to Suitland (Maryland) | 702.71 mi (1,130.91 km) |
| Edwardsville to Sulphur (Louisiana) | 621.87 mi (1,000.80 km) |
| Edwardsville to Sulphur Springs (Texas) | 501.10 mi (806.45 km) |
| Edwardsville to Summerfield (Maryland) | 705.41 mi (1,135.24 km) |
| Edwardsville to Summerfield (North Carolina) | 580.96 mi (934.97 km) |
| Edwardsville to Summerlin South (Nevada) | 1,397.69 mi (2,249.37 km) |
| Edwardsville to Summerville (South Carolina) | 678.59 mi (1,092.09 km) |
| Edwardsville to Summit (Illinois) | 236.52 mi (380.63 km) |
| Edwardsville to Summit (New Jersey) | 839.27 mi (1,350.68 km) |
| Edwardsville to Sumner (Washington) | 1,715.63 mi (2,761.05 km) |
