| Edwardsville to Robertsville (New Jersey) | 841.57 mi (1,354.37 km) |
| Edwardsville to Robinson (Texas) | 647.46 mi (1,041.99 km) |
| Edwardsville to Robstown (Texas) | 879.09 mi (1,414.76 km) |
| Edwardsville to Rochester (Michigan) | 448.81 mi (722.30 km) |
| Edwardsville to Rochester (Minnesota) | 383.22 mi (616.74 km) |
| Edwardsville to Rochester (New Hampshire) | 1,035.64 mi (1,666.71 km) |
| Edwardsville to Rochester (New York) | 711.66 mi (1,145.30 km) |
| Edwardsville to Rochester Hills (Michigan) | 446.42 mi (718.45 km) |
| Edwardsville to Rock Hill (South Carolina) | 562.00 mi (904.45 km) |
| Edwardsville to Rock Island (Illinois) | 187.66 mi (302.01 km) |
| Edwardsville to Rock Springs (Wyoming) | 1,031.14 mi (1,659.46 km) |
| Edwardsville to Rockford (Illinois) | 244.43 mi (393.37 km) |
| Edwardsville to Rockledge (Florida) | 897.35 mi (1,444.14 km) |
| Edwardsville to Rocklin (California) | 1,675.01 mi (2,695.66 km) |
| Edwardsville to Rockport (Texas) | 847.83 mi (1,364.44 km) |
