| Edwardsville to Rancho Cordova (California) | 1,678.06 mi (2,700.58 km) |
| Edwardsville to Rancho Cucamonga (California) | 1,559.88 mi (2,510.39 km) |
| Edwardsville to Rancho Mirage (California) | 1,507.40 mi (2,425.93 km) |
| Edwardsville to Rancho Palos Verdes (California) | 1,611.57 mi (2,593.57 km) |
| Edwardsville to Rancho San Diego (California) | 1,559.75 mi (2,510.18 km) |
| Edwardsville to Rancho Santa Margarita (California) | 1,573.54 mi (2,532.37 km) |
| Edwardsville to Randallstown (Maryland) | 707.66 mi (1,138.86 km) |
| Edwardsville to Rantoul (Illinois) | 142.93 mi (230.02 km) |
| Edwardsville to Rapid City (South Dakota) | 775.20 mi (1,247.57 km) |
| Edwardsville to Ravenna (Ohio) | 490.84 mi (789.92 km) |
| Edwardsville to Raymondville (Texas) | 963.18 mi (1,550.09 km) |
| Edwardsville to Raymore (Missouri) | 240.73 mi (387.42 km) |
| Edwardsville to Raytown (Missouri) | 241.12 mi (388.05 km) |
| Edwardsville to Reading (Ohio) | 299.64 mi (482.22 km) |
| Edwardsville to Reading (Pennsylvania) | 755.69 mi (1,216.17 km) |
