| Edwardsville to Punta Gorda (Florida) | 941.39 mi (1,515.03 km) |
| Edwardsville to Puyallup (Washington) | 1,717.88 mi (2,764.66 km) |
| Edwardsville to Queen Creek (Arizona) | 1,264.52 mi (2,035.05 km) |
| Edwardsville to Queens (New York) | 869.05 mi (1,398.61 km) |
| Edwardsville to Quincy (Illinois) | 108.41 mi (174.46 km) |
| Edwardsville to Quincy (Massachusetts) | 1,022.18 mi (1,645.05 km) |
| Edwardsville to Raceland (Louisiana) | 627.35 mi (1,009.62 km) |
| Edwardsville to Racine (Wisconsin) | 294.71 mi (474.29 km) |
| Edwardsville to Radcliff (Kentucky) | 229.64 mi (369.57 km) |
| Edwardsville to Radford (Virginia) | 526.18 mi (846.80 km) |
| Edwardsville to Rahway (New Jersey) | 843.18 mi (1,356.97 km) |
| Edwardsville to Raleigh (North Carolina) | 655.56 mi (1,055.02 km) |
| Edwardsville to Ramona (California) | 1,549.81 mi (2,494.18 km) |
| Edwardsville to Ramsey (Minnesota) | 480.90 mi (773.93 km) |
| Edwardsville to Ramsey (New Jersey) | 852.64 mi (1,372.20 km) |
