| Edwardsville to Monticello (Minnesota) | 490.14 mi (788.80 km) |
| Edwardsville to Montrose (Colorado) | 963.34 mi (1,550.35 km) |
| Edwardsville to Moody (Alabama) | 408.15 mi (656.86 km) |
| Edwardsville to Moore (Oklahoma) | 476.95 mi (767.58 km) |
| Edwardsville to Moorestown-Lenola (New Jersey) | 805.46 mi (1,296.26 km) |
| Edwardsville to Mooresville (North Carolina) | 550.45 mi (885.86 km) |
| Edwardsville to Moorhead (Minnesota) | 654.08 mi (1,052.64 km) |
| Edwardsville to Moorpark (California) | 1,626.60 mi (2,617.75 km) |
| Edwardsville to Moraga (California) | 1,734.27 mi (2,791.03 km) |
| Edwardsville to Moreno Valley (California) | 1,545.20 mi (2,486.76 km) |
| Edwardsville to Morgan City (Louisiana) | 631.67 mi (1,016.57 km) |
| Edwardsville to Morgan Hill (California) | 1,719.56 mi (2,767.37 km) |
| Edwardsville to Morganton (North Carolina) | 501.83 mi (807.61 km) |
| Edwardsville to Morgantown (West Virginia) | 540.39 mi (869.68 km) |
| Edwardsville to Morris (Illinois) | 196.51 mi (316.25 km) |
