| Edwardsville to Mitchell (South Dakota) | 539.01 mi (867.46 km) |
| Edwardsville to Mitchellville (Maryland) | 708.13 mi (1,139.63 km) |
| Edwardsville to Moberly (Missouri) | 138.23 mi (222.46 km) |
| Edwardsville to Mobile (Alabama) | 570.56 mi (918.23 km) |
| Edwardsville to Modesto (California) | 1,677.53 mi (2,699.72 km) |
| Edwardsville to Mokena (Illinois) | 219.66 mi (353.51 km) |
| Edwardsville to Moline (Illinois) | 187.75 mi (302.16 km) |
| Edwardsville to Moncks Corner (South Carolina) | 678.94 mi (1,092.65 km) |
| Edwardsville to Monfort Heights (Ohio) | 290.14 mi (466.94 km) |
| Edwardsville to Monmouth (Oregon) | 1,748.83 mi (2,814.48 km) |
| Edwardsville to Monroe (Georgia) | 490.65 mi (789.63 km) |
| Edwardsville to Monroe (Louisiana) | 449.03 mi (722.65 km) |
| Edwardsville to Monroe (Michigan) | 408.99 mi (658.21 km) |
| Edwardsville to Monroe (North Carolina) | 582.49 mi (937.42 km) |
| Edwardsville to Monroe (Ohio) | 304.61 mi (490.23 km) |
