| Edwardsville to Merrick (New York) | 881.42 mi (1,418.51 km) |
| Edwardsville to Merrifield (Virginia) | 685.42 mi (1,103.08 km) |
| Edwardsville to Merrillville (Indiana) | 232.70 mi (374.50 km) |
| Edwardsville to Merritt Island (Florida) | 899.93 mi (1,448.30 km) |
| Edwardsville to Mesa (Arizona) | 1,265.52 mi (2,036.66 km) |
| Edwardsville to Mesquite (Nevada) | 1,321.53 mi (2,126.80 km) |
| Edwardsville to Mesquite (Texas) | 556.92 mi (896.28 km) |
| Edwardsville to Metairie (Louisiana) | 607.74 mi (978.06 km) |
| Edwardsville to Methuen Town (Massachusetts) | 1,018.35 mi (1,638.87 km) |
| Edwardsville to Metuchen (New Jersey) | 838.61 mi (1,349.62 km) |
| Edwardsville to Mexico (Missouri) | 104.37 mi (167.96 km) |
| Edwardsville to Miami (Florida) | 1,063.31 mi (1,711.23 km) |
| Edwardsville to Miami (Oklahoma) | 297.14 mi (478.19 km) |
| Edwardsville to Miami Beach (Florida) | 1,063.53 mi (1,711.58 km) |
| Edwardsville to Miami Gardens (Florida) | 1,052.77 mi (1,694.27 km) |
