| Edwardsville to McKeesport (Pennsylvania) | 550.44 mi (885.85 km) |
| Edwardsville to McKinleyville (California) | 1,802.85 mi (2,901.41 km) |
| Edwardsville to McKinney (Texas) | 536.92 mi (864.09 km) |
| Edwardsville to McLean (Virginia) | 687.73 mi (1,106.79 km) |
| Edwardsville to McMinnville (Oregon) | 1,748.13 mi (2,813.34 km) |
| Edwardsville to McMinnville (Tennessee) | 315.49 mi (507.73 km) |
| Edwardsville to McNair (Virginia) | 676.05 mi (1,087.99 km) |
| Edwardsville to McPherson (Kansas) | 415.33 mi (668.41 km) |
| Edwardsville to Mead Valley (California) | 1,551.75 mi (2,497.29 km) |
| Edwardsville to Meadow Woods (Florida) | 874.20 mi (1,406.88 km) |
| Edwardsville to Meadowbrook (Virginia) | 686.20 mi (1,104.33 km) |
| Edwardsville to Meadville (Pennsylvania) | 554.98 mi (893.16 km) |
| Edwardsville to Mebane (North Carolina) | 616.36 mi (991.93 km) |
| Edwardsville to Mechanicsville (Virginia) | 689.91 mi (1,110.31 km) |
| Edwardsville to Medford (Massachusetts) | 1,019.19 mi (1,640.23 km) |
