| Edwardsville to Livermore (California) | 1,717.28 mi (2,763.70 km) |
| Edwardsville to Livingston (California) | 1,666.44 mi (2,681.87 km) |
| Edwardsville to Livonia (Michigan) | 426.93 mi (687.08 km) |
| Edwardsville to Lochearn (Maryland) | 711.52 mi (1,145.08 km) |
| Edwardsville to Lockhart (Florida) | 856.32 mi (1,378.11 km) |
| Edwardsville to Lockhart (Texas) | 755.68 mi (1,216.16 km) |
| Edwardsville to Lockport (Illinois) | 219.22 mi (352.80 km) |
| Edwardsville to Lockport (New York) | 661.33 mi (1,064.30 km) |
| Edwardsville to Lodi (California) | 1,686.13 mi (2,713.56 km) |
| Edwardsville to Lodi (New Jersey) | 854.89 mi (1,375.81 km) |
| Edwardsville to Logan (Utah) | 1,166.79 mi (1,877.77 km) |
| Edwardsville to Logansport (Indiana) | 235.59 mi (379.15 km) |
| Edwardsville to Loganville (Georgia) | 481.76 mi (775.32 km) |
| Edwardsville to Loma Linda (California) | 1,544.74 mi (2,486.02 km) |
| Edwardsville to Lombard (Illinois) | 236.89 mi (381.24 km) |
