| Edwardsville to Lawndale (California) | 1,607.79 mi (2,587.49 km) |
| Edwardsville to Lawrence (Indiana) | 226.14 mi (363.94 km) |
| Edwardsville to Lawrence (Kansas) | 284.03 mi (457.11 km) |
| Edwardsville to Lawrence (Massachusetts) | 1,019.29 mi (1,640.40 km) |
| Edwardsville to Lawrenceburg (Kentucky) | 280.17 mi (450.89 km) |
| Edwardsville to Lawrenceburg (Tennessee) | 285.20 mi (458.98 km) |
| Edwardsville to Lawrenceville (Georgia) | 472.04 mi (759.67 km) |
| Edwardsville to Lawton (Oklahoma) | 548.64 mi (882.95 km) |
| Edwardsville to Layton (Utah) | 1,171.68 mi (1,885.63 km) |
| Edwardsville to Le Mars (Iowa) | 424.85 mi (683.73 km) |
| Edwardsville to League City (Texas) | 706.13 mi (1,136.41 km) |
| Edwardsville to Lealman (Florida) | 866.75 mi (1,394.90 km) |
| Edwardsville to Leander (Texas) | 722.32 mi (1,162.46 km) |
| Edwardsville to Leavenworth (Kansas) | 267.36 mi (430.27 km) |
| Edwardsville to Leawood (Kansas) | 249.69 mi (401.84 km) |
