| Edwardsville to Largo (Florida) | 858.86 mi (1,382.21 km) |
| Edwardsville to Largo (Maryland) | 707.60 mi (1,138.77 km) |
| Edwardsville to Larkspur (California) | 1,754.66 mi (2,823.85 km) |
| Edwardsville to Las Cruces (New Mexico) | 1,042.55 mi (1,677.82 km) |
| Edwardsville to Las Vegas (Nevada) | 1,392.13 mi (2,240.41 km) |
| Edwardsville to Las Vegas (New Mexico) | 865.74 mi (1,393.27 km) |
| Edwardsville to Latham (New York) | 890.79 mi (1,433.59 km) |
| Edwardsville to Lathrop (California) | 1,691.59 mi (2,722.35 km) |
| Edwardsville to Lauderdale Lakes (Florida) | 1,040.65 mi (1,674.77 km) |
| Edwardsville to Lauderhill (Florida) | 1,040.40 mi (1,674.36 km) |
| Edwardsville to Laurel (Florida) | 914.40 mi (1,471.58 km) |
| Edwardsville to Laurel (Maryland) | 705.02 mi (1,134.63 km) |
| Edwardsville to Laurel (Mississippi) | 492.62 mi (792.79 km) |
| Edwardsville to Laurel (Virginia) | 681.70 mi (1,097.09 km) |
| Edwardsville to Laurinburg (North Carolina) | 644.37 mi (1,037.02 km) |
