| Edwardsville to Hormigueros (Puerto Rico) | 1,979.65 mi (3,185.94 km) |
| Edwardsville to Horn Lake (Mississippi) | 265.41 mi (427.14 km) |
| Edwardsville to Hot Springs (Arkansas) | 342.32 mi (550.91 km) |
| Edwardsville to Hot Springs Village (Arkansas) | 329.84 mi (530.82 km) |
| Edwardsville to Houma (Louisiana) | 637.82 mi (1,026.47 km) |
| Edwardsville to Houston (Texas) | 694.11 mi (1,117.06 km) |
| Edwardsville to Howard (Wisconsin) | 410.99 mi (661.43 km) |
| Edwardsville to Huber Heights (Ohio) | 322.45 mi (518.93 km) |
| Edwardsville to Hudson (Florida) | 833.60 mi (1,341.54 km) |
| Edwardsville to Hudson (Ohio) | 482.58 mi (776.63 km) |
| Edwardsville to Hudson (Wisconsin) | 449.10 mi (722.76 km) |
| Edwardsville to Hueytown (Alabama) | 406.11 mi (653.57 km) |
| Edwardsville to Hugo (Minnesota) | 466.06 mi (750.06 km) |
| Edwardsville to Humacao (Puerto Rico) | 2,033.87 mi (3,273.20 km) |
| Edwardsville to Humble (Texas) | 678.09 mi (1,091.28 km) |
