| Edwardsville to Homer Glen (Illinois) | 222.05 mi (357.36 km) |
| Edwardsville to Homestead (Florida) | 1,075.19 mi (1,730.36 km) |
| Edwardsville to Homewood (Alabama) | 408.70 mi (657.74 km) |
| Edwardsville to Homewood (Illinois) | 227.20 mi (365.65 km) |
| Edwardsville to Homosassa Springs (Florida) | 810.69 mi (1,304.67 km) |
| Edwardsville to Honeygo (Maryland) | 727.60 mi (1,170.96 km) |
| Edwardsville to Honolulu (Hawaii) | 4,138.67 mi (6,660.55 km) |
| Edwardsville to Hoover (Alabama) | 414.13 mi (666.48 km) |
| Edwardsville to Hopatcong (New Jersey) | 825.28 mi (1,328.16 km) |
| Edwardsville to Hope Mills (North Carolina) | 663.60 mi (1,067.96 km) |
| Edwardsville to Hopewell (Virginia) | 697.62 mi (1,122.72 km) |
| Edwardsville to Hopkins (Minnesota) | 458.74 mi (738.27 km) |
| Edwardsville to Hopkinsville (Kentucky) | 192.33 mi (309.53 km) |
| Edwardsville to Horizon City (Texas) | 1,035.89 mi (1,667.10 km) |
| Edwardsville to Horizon West (Florida) | 861.35 mi (1,386.21 km) |
