| Edwardsville to Friendswood (Texas) | 706.76 mi (1,137.42 km) |
| Edwardsville to Frisco (Texas) | 545.27 mi (877.53 km) |
| Edwardsville to Front Royal (Virginia) | 634.69 mi (1,021.43 km) |
| Edwardsville to Fruit Cove (Florida) | 766.28 mi (1,233.20 km) |
| Edwardsville to Fruita (Colorado) | 1,005.32 mi (1,617.90 km) |
| Edwardsville to Fruitville (Florida) | 902.93 mi (1,453.12 km) |
| Edwardsville to Fuller Heights (Florida) | 880.36 mi (1,416.81 km) |
| Edwardsville to Fullerton (California) | 1,585.04 mi (2,550.88 km) |
| Edwardsville to Fullerton (Pennsylvania) | 780.37 mi (1,255.89 km) |
| Edwardsville to Fulshear (Texas) | 712.70 mi (1,146.99 km) |
| Edwardsville to Fulton (Missouri) | 105.79 mi (170.25 km) |
| Edwardsville to Fulton (New York) | 771.89 mi (1,242.24 km) |
| Edwardsville to Fuquay-Varina (North Carolina) | 654.77 mi (1,053.76 km) |
| Edwardsville to Gadsden (Alabama) | 397.42 mi (639.59 km) |
| Edwardsville to Gaffney (South Carolina) | 526.70 mi (847.65 km) |
