| Edwardsville to Firestone (Colorado) | 802.56 mi (1,291.59 km) |
| Edwardsville to Fish Hawk (Florida) | 878.21 mi (1,413.35 km) |
| Edwardsville to Fishers (Indiana) | 229.39 mi (369.16 km) |
| Edwardsville to Fitchburg (Massachusetts) | 985.33 mi (1,585.74 km) |
| Edwardsville to Fitchburg (Wisconsin) | 291.24 mi (468.70 km) |
| Edwardsville to Five Corners (Washington) | 1,720.33 mi (2,768.60 km) |
| Edwardsville to Five Forks (South Carolina) | 509.76 mi (820.38 km) |
| Edwardsville to Flagstaff (Arizona) | 1,216.47 mi (1,957.73 km) |
| Edwardsville to Flat Rock (Michigan) | 420.40 mi (676.56 km) |
| Edwardsville to Fleming Island (Florida) | 762.85 mi (1,227.69 km) |
| Edwardsville to Flint (Michigan) | 439.69 mi (707.62 km) |
| Edwardsville to Floral Park (New York) | 873.89 mi (1,406.38 km) |
| Edwardsville to Florence (Alabama) | 302.35 mi (486.58 km) |
| Edwardsville to Florence (Arizona) | 1,259.41 mi (2,026.82 km) |
| Edwardsville to Florence (Kentucky) | 287.47 mi (462.65 km) |
