| Edwardsville to Elkhorn (Wisconsin) | 278.55 mi (448.28 km) |
| Edwardsville to Elko (Nevada) | 1,370.51 mi (2,205.62 km) |
| Edwardsville to Elkridge (Maryland) | 711.15 mi (1,144.49 km) |
| Edwardsville to Elkton (Maryland) | 759.82 mi (1,222.82 km) |
| Edwardsville to Ellensburg (Washington) | 1,634.97 mi (2,631.23 km) |
| Edwardsville to Ellicott City (Maryland) | 706.08 mi (1,136.32 km) |
| Edwardsville to Elmhurst (Illinois) | 240.01 mi (386.27 km) |
| Edwardsville to Elmira (New York) | 728.61 mi (1,172.59 km) |
| Edwardsville to Elmont (New York) | 873.55 mi (1,405.84 km) |
| Edwardsville to Elmwood Park (Illinois) | 244.61 mi (393.66 km) |
| Edwardsville to Elmwood Park (New Jersey) | 853.02 mi (1,372.80 km) |
| Edwardsville to Elon (North Carolina) | 603.70 mi (971.56 km) |
| Edwardsville to Eloy (Arizona) | 1,277.84 mi (2,056.49 km) |
| Edwardsville to Elwood (New York) | 893.43 mi (1,437.83 km) |
| Edwardsville to Elyria (Ohio) | 453.05 mi (729.11 km) |
