| Edwardsville to East Lake (Florida) | 848.24 mi (1,365.11 km) |
| Edwardsville to East Lake-Orient Park (Florida) | 865.01 mi (1,392.11 km) |
| Edwardsville to East Lansing (Michigan) | 396.88 mi (638.71 km) |
| Edwardsville to East Los Angeles (California) | 1,594.45 mi (2,566.02 km) |
| Edwardsville to East Massapequa (New York) | 887.66 mi (1,428.55 km) |
| Edwardsville to East Meadow (New York) | 881.32 mi (1,418.35 km) |
| Edwardsville to East Milton (Florida) | 590.25 mi (949.91 km) |
| Edwardsville to East Moline (Illinois) | 189.65 mi (305.21 km) |
| Edwardsville to East Niles (California) | 1,605.58 mi (2,583.94 km) |
| Edwardsville to East Northport (New York) | 894.39 mi (1,439.38 km) |
| Edwardsville to East Orange (New Jersey) | 847.50 mi (1,363.93 km) |
| Edwardsville to East Palo Alto (California) | 1,740.63 mi (2,801.27 km) |
| Edwardsville to East Patchogue (New York) | 911.76 mi (1,467.34 km) |
| Edwardsville to East Peoria (Illinois) | 132.13 mi (212.64 km) |
| Edwardsville to East Point (Georgia) | 468.65 mi (754.23 km) |
