| Edwardsville to Dover (New Hampshire) | 1,038.88 mi (1,671.91 km) |
| Edwardsville to Dover (New Jersey) | 830.03 mi (1,335.81 km) |
| Edwardsville to Dover (Ohio) | 467.93 mi (753.06 km) |
| Edwardsville to Downers Grove (Illinois) | 231.98 mi (373.34 km) |
| Edwardsville to Downey (California) | 1,594.67 mi (2,566.37 km) |
| Edwardsville to Dranesville (Virginia) | 678.15 mi (1,091.38 km) |
| Edwardsville to Draper (Utah) | 1,166.65 mi (1,877.54 km) |
| Edwardsville to Drexel Heights (Arizona) | 1,267.31 mi (2,039.54 km) |
| Edwardsville to Drexel Hill (Pennsylvania) | 787.46 mi (1,267.29 km) |
| Edwardsville to Duarte (California) | 1,579.66 mi (2,542.22 km) |
| Edwardsville to Dublin (California) | 1,724.08 mi (2,774.64 km) |
| Edwardsville to Dublin (Georgia) | 586.02 mi (943.11 km) |
| Edwardsville to Dublin (Ohio) | 376.12 mi (605.31 km) |
| Edwardsville to Dubuque (Iowa) | 258.96 mi (416.75 km) |
| Edwardsville to Duluth (Georgia) | 463.27 mi (745.56 km) |
