| Edwardsville to Dixon (California) | 1,710.09 mi (2,752.12 km) |
| Edwardsville to Dixon (Illinois) | 212.54 mi (342.05 km) |
| Edwardsville to Dobbs Ferry (New York) | 866.66 mi (1,394.76 km) |
| Edwardsville to Doctor Phillips (Florida) | 864.97 mi (1,392.04 km) |
| Edwardsville to Dodge City (Kansas) | 548.43 mi (882.62 km) |
| Edwardsville to Dolton (Illinois) | 233.00 mi (374.97 km) |
| Edwardsville to Donna (Texas) | 991.20 mi (1,595.19 km) |
| Edwardsville to Dorado (Puerto Rico) | 1,998.13 mi (3,215.68 km) |
| Edwardsville to Doral (Florida) | 1,056.92 mi (1,700.95 km) |
| Edwardsville to Doraville (Georgia) | 463.59 mi (746.08 km) |
| Edwardsville to Dothan (Alabama) | 582.82 mi (937.95 km) |
| Edwardsville to Douglas (Arizona) | 1,215.64 mi (1,956.38 km) |
| Edwardsville to Douglas (Georgia) | 644.34 mi (1,036.97 km) |
| Edwardsville to Douglasville (Georgia) | 456.45 mi (734.59 km) |
| Edwardsville to Dover (Delaware) | 776.68 mi (1,249.94 km) |
