| Edwardsville to Cullman (Alabama) | 363.56 mi (585.09 km) |
| Edwardsville to Culpeper (Virginia) | 646.92 mi (1,041.12 km) |
| Edwardsville to Culver City (California) | 1,607.33 mi (2,586.75 km) |
| Edwardsville to Cumberland (Maryland) | 603.58 mi (971.36 km) |
| Edwardsville to Cupertino (California) | 1,738.26 mi (2,797.45 km) |
| Edwardsville to Cutler Bay (Florida) | 1,071.92 mi (1,725.09 km) |
| Edwardsville to Cutlerville (Michigan) | 359.22 mi (578.11 km) |
| Edwardsville to Cuyahoga Falls (Ohio) | 477.04 mi (767.72 km) |
| Edwardsville to Cypress (California) | 1,592.61 mi (2,563.06 km) |
| Edwardsville to Cypress Gardens (Florida) | 885.03 mi (1,424.32 km) |
| Edwardsville to Cypress Lake (Florida) | 967.48 mi (1,557.01 km) |
| Edwardsville to D'Iberville (Mississippi) | 578.24 mi (930.59 km) |
| Edwardsville to Dakota Ridge (Colorado) | 812.00 mi (1,306.79 km) |
| Edwardsville to Dale City (Virginia) | 681.00 mi (1,095.97 km) |
| Edwardsville to Dallas (Georgia) | 442.03 mi (711.38 km) |
