| Edwardsville to Commerce (California) | 1,594.39 mi (2,565.93 km) |
| Edwardsville to Commerce City (Colorado) | 796.49 mi (1,281.82 km) |
| Edwardsville to Compton (California) | 1,600.93 mi (2,576.44 km) |
| Edwardsville to Comstock Park (Michigan) | 369.91 mi (595.32 km) |
| Edwardsville to Concord (California) | 1,725.97 mi (2,777.67 km) |
| Edwardsville to Concord (Missouri) | 27.82 mi (44.78 km) |
| Edwardsville to Concord (New Hampshire) | 1,006.06 mi (1,619.10 km) |
| Edwardsville to Concord (North Carolina) | 565.94 mi (910.80 km) |
| Edwardsville to Conneaut (Ohio) | 540.75 mi (870.25 km) |
| Edwardsville to Connersville (Indiana) | 266.17 mi (428.37 km) |
| Edwardsville to Conroe (Texas) | 663.07 mi (1,067.11 km) |
| Edwardsville to Converse (Texas) | 797.79 mi (1,283.91 km) |
| Edwardsville to Conway (Arkansas) | 291.07 mi (468.43 km) |
| Edwardsville to Conway (Florida) | 867.29 mi (1,395.77 km) |
| Edwardsville to Conway (South Carolina) | 698.08 mi (1,123.45 km) |
