| Edwardsville to Clemson (South Carolina) | 488.01 mi (785.38 km) |
| Edwardsville to Clermont (Florida) | 852.63 mi (1,372.17 km) |
| Edwardsville to Cleveland (Mississippi) | 351.23 mi (565.25 km) |
| Edwardsville to Cleveland (Ohio) | 476.13 mi (766.25 km) |
| Edwardsville to Cleveland (Tennessee) | 376.68 mi (606.20 km) |
| Edwardsville to Cleveland Heights (Ohio) | 482.64 mi (776.73 km) |
| Edwardsville to Cliffside Park (New Jersey) | 859.47 mi (1,383.18 km) |
| Edwardsville to Clifton (Colorado) | 991.33 mi (1,595.39 km) |
| Edwardsville to Clifton (New Jersey) | 850.84 mi (1,369.29 km) |
| Edwardsville to Clinton (Iowa) | 211.25 mi (339.97 km) |
| Edwardsville to Clinton (Maryland) | 704.07 mi (1,133.09 km) |
| Edwardsville to Clinton (Mississippi) | 445.28 mi (716.60 km) |
| Edwardsville to Clinton (Utah) | 1,177.11 mi (1,894.38 km) |
| Edwardsville to Clive (Iowa) | 280.06 mi (450.72 km) |
| Edwardsville to Cloquet (Minnesota) | 562.36 mi (905.04 km) |
