| Edwardsville to Channelview (Texas) | 687.00 mi (1,105.62 km) |
| Edwardsville to Chantilly (Virginia) | 674.48 mi (1,085.47 km) |
| Edwardsville to Chaparral (New Mexico) | 1,033.24 mi (1,662.84 km) |
| Edwardsville to Chapel Hill (North Carolina) | 632.53 mi (1,017.95 km) |
| Edwardsville to Charleston (Illinois) | 108.11 mi (173.98 km) |
| Edwardsville to Charleston (South Carolina) | 696.15 mi (1,120.34 km) |
| Edwardsville to Charleston (West Virginia) | 452.23 mi (727.80 km) |
| Edwardsville to Charlotte (North Carolina) | 562.33 mi (904.98 km) |
| Edwardsville to Charlottesville (Virginia) | 624.44 mi (1,004.94 km) |
| Edwardsville to Chaska (Minnesota) | 455.99 mi (733.85 km) |
| Edwardsville to Chatham (Illinois) | 62.88 mi (101.19 km) |
| Edwardsville to Chattanooga (Tennessee) | 367.05 mi (590.70 km) |
| Edwardsville to Cheat Lake (West Virginia) | 545.28 mi (877.55 km) |
| Edwardsville to Chelsea (Alabama) | 421.57 mi (678.46 km) |
| Edwardsville to Chelsea (Massachusetts) | 1,022.79 mi (1,646.02 km) |
